Further Characterization of Painful Constipation (PC)
| Autor: | Christine B. Dalton, Nicolas Diamante, Brenda B. Toner, Shrikant I. Bangdiwala, Carolyn B. Morris, Douglas A. Drossman, Jane Leserman, Yuming Hu |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Diarrhea medicine.medical_specialty Constipation Adolescent Visual analogue scale Health Status medicine.medical_treatment Population Laxative Antidepressive Agents Tricyclic Severity of Illness Index Gastroenterology Irritable Bowel Syndrome Young Adult Bloating Patient Education as Topic Surveys and Questionnaires Internal medicine medicine Humans Defecation education Irritable bowel syndrome Aged education.field_of_study Cognitive Behavioral Therapy business.industry Desipramine Repeated measures design Middle Aged medicine.disease Abdominal Pain Treatment Outcome Functional constipation Female medicine.symptom business |
| Zdroj: | Journal of Clinical Gastroenterology. 42:1080-1088 |
| ISSN: | 0192-0790 |
| DOI: | 10.1097/mcg.0b013e31815146f9 |
| Popis: | Background: There has been some question about the classification of painful constipation (PC) and its relationship to irritable bowel syndrome (IBS), and in particular IBS with constipation (IBS-C). We sought to: (1) compare PC with IBS and its subtypes (IBS-C, IBS-D, and IBS-A) in terms of pain scores, stool habit and clinical features, and to determine which factors predict PC over IBS, (2) determine the variation in pain and stool habit for PC relative to IBS over time, and (3) compare whether there are clinical differences between those with high pain constipation (HPC) and low pain constipation (LPC) over time. Methods: Among 231 women in an National Institutes of Health trial, Rome II moderate to severe PC (n = 41), IBS-A (n = 55), IBS-C (n = 80), and IBS-D (n = 55) received diary cards on stool frequency, consistency, and pain (visual analog scale) daily for 14 days before and after 12-week treatment and at 3-month intervals for 1 year. PC was characterized into HPC (high pain) and LPC (low pain) groups based on visual analog scale pain scores (high pain > 50 and low pain |
| Databáze: | OpenAIRE |
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