Actions and interactions of the IGF system in Alzheimer’s disease: review and hypotheses
| Autor: | Donald M. Henricks, Sandra L. Gray, Brett R. Lackey |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
Proteases Endocrinology Diabetes and Metabolism medicine.medical_treatment Apoptosis Disease Mitochondrion Biology DNA-binding protein Endocrinology Alzheimer Disease Somatomedins Internal medicine medicine Humans Insulin Receptor Neurons medicine.disease Somatomedin Immunity Innate Mitochondria Cytokine Proto-Oncogene Proteins c-bcl-2 Caspases Alzheimer's disease Neuroscience |
| Zdroj: | Growth Hormone & IGF Research. 10:1-13 |
| ISSN: | 1096-6374 |
| Popis: | Insulin-like growth factors (IGF) are pleiotrophic polypeptides affecting all aspects of growth and development. The IGF system, including ligands, receptors, binding proteins and proteases is also involved in pathophysiological conditions, such as cancer and degenerative conditions. In this review, the actions and interactions of the IGF system as it relates to Alzheimer's disease will be investigated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect