The Effect of Tsukamurella inchonensis Bacterin on the Immune Response Against Influenza and Newcastle Disease Vaccines in Broiler Chickens
| Autor: | Mansoor Mayahi, Ebrahim Golzari, katayoon nofouzi, Rahil Chegini, Forough Talazadeh |
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| Rok vydání: | 2016 |
| Předmět: |
animal structures
animal diseases Newcastle disease virus 030204 cardiovascular system & hematology medicine.disease_cause complex mixtures Newcastle disease 03 medical and health sciences 0302 clinical medicine Immune system Immunity medicine lcsh:RC799-869 broiler chickens response biology Tsukamurella inchonensis Antibody titer Avian Influenza Virus (AIV) biology.organism_classification Virology Influenza A virus subtype H5N1 Vaccination 030220 oncology & carcinogenesis Immunology lcsh:Diseases of the digestive system. Gastroenterology immune Mycobacterium vaccae Tsukamurella inchonensis bacterin |
| Zdroj: | International Journal of Enteric Pathogens, Vol 4, Iss 4, p e37107 (2016) |
| ISSN: | 2322-5866 2345-3362 |
| DOI: | 10.15171/ijep.2016.17 |
| Popis: | Background: In poultry production, improving immunity is very important to prevent infectious diseases. One solution to improve the immunity of animals and to decrease their susceptibility to infectious disease is administration of immunostimulants. Surveys have indicated that some bacteria can work as immunomodulators such as Mycobacterium vaccae and can promote Th1-mediated mechanisms, and switch off pre-existing Th2 preponderance (1). Objectives: The aim of this study was to examine the effect of Tsukamurella inchonensis bacterin on the immune response against Influenza and Newcastle disease vaccine in broiler chickens . Materials and Methods: A total of 170 day-old broiler chicks were purchased and divided randomly into 5 equal groups. Chickens of group A received 106 bacterin subcutaneously on two days before vaccination against Newcastle disease and avian influenza. Chickens of group B received 106 bacterin subcutaneously on six days after the first injection of bacterin. Chickens of group C received 106bacterin subcutaneously on six days after the second injection of bacterin. Chickens of group D, vaccinated against Newcastle disease and avian influenza but did not receive bacterin. Chickens of group E, did not vaccinate against Newcastle disease and avian influenza and did not receive bacterin. All groups except group E, were vaccinated with live Newcastle vaccine and AI-ND killed vaccine (subtype H9N2). Blood samples were collected and antibody titer against Newcastle disease vaccine and avian influenza vaccine was determined by HI test. Results: The results of present study showed that receiving of Tsukamurella inchonensis bacterin for 3 times, significantly increased the specific antibody response to avian influenza subtype H9N2 vaccine. Also about Newcastle vaccine, significantly increased the specific antibody response to Newcastle vaccine at 21 and 28 days after vaccination. Conclusions: Receiving of Tsukamurella inchonensis bacterin can enhance immune response against NDV and AIV. |
| Databáze: | OpenAIRE |
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