Study on the resistance of severe acute respiratory syndrome-associated coronavirus

Autor: Chao Liu, Bao Zhong Guo, Wen Jun Xiao, Gui Jie Wang, Fu Huan Chao, Min Nian Wang, Nong Song, Jun Wen Li, Wei Wei, Jin Song Li, Guo Rong Ou, Bing Yin Si, Tong Yu Fang, Jing Yin, Xin Wei Wang, Bei Zhen, Min Jin, Qing Xin Kong
Rok vydání: 2005
Předmět:
Zdroj: Journal of Virological Methods
ISSN: 0166-0934
DOI: 10.1016/j.jviromet.2005.02.005
Popis: In this study, the persistence of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) was observed in feces, urine and water. In addition, the inactivation of SARS-CoV in wastewater with sodium hypochlorite and chlorine dioxide was also studied. In vitro experiments demonstrated that the virus could only persist for 2 days in hospital wastewater, domestic sewage and dechlorinated tap water, while 3 days in feces, 14 days in PBS and 17 days in urine at 20 degrees C. However, at 4 degrees C, the SARS-CoV could persist for 14 days in wastewater and at least 17 days in feces or urine. SARS-CoV is more susceptible to disinfectants than Escherichia coli and f2 phage. Free chlorine was found to inactivate SARS-CoV better than chlorine dioxide. Free residue chlorine over 0.5 mg/L for chlorine or 2.19 mg/L for chlorine dioxide in wastewater ensures complete inactivation of SARS-CoV while it does not inactivate completely E. coli and f2 phage.
Databáze: OpenAIRE