An Assessment of In Ovo Toxicity of the Flame Retardant 1,2-Dibromo-4-(1,2-Dibromoethyl) Cyclohexane (TBECH) in the Zebra Finch
| Autor: | John E. Elliott, Heidi A. Currier, Robert J. Letcher, Tony D. Williams |
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| Rok vydání: | 2013 |
| Předmět: |
animal structures
food.ingredient Health Toxicology and Mutagenesis Poison control Toxicology In ovo Andrology food Cyclohexanes Yolk Animals Zebra finch Flame Retardants Ovum biology Chemistry General Medicine biology.organism_classification Pollution embryonic structures Toxicity Brominated flame retardant Environmental Pollutants Female Finches Taeniopygia Fire retardant |
| Zdroj: | Bulletin of Environmental Contamination and Toxicology. 91:455-459 |
| ISSN: | 1432-0800 0007-4861 |
| DOI: | 10.1007/s00128-013-1070-z |
| Popis: | Embryonic toxicity of a brominated flame retardant, TBECH (1,2-dibromo-4-(1, 2-dibromoethyl) cyclohexane) was investigated using the zebra finch (Taeniopygia guttata) as our model. Using in ovo dosing procedures, we injected the technical TBECH compound, consisting of 50:50 α-/β-isomers, directly into the yolk of freshly laid eggs at concentrations of 2.3-94 ng/g egg. No significant effects were observed in terms of growth or survival for either pre-hatch embryos or post-hatch chicks. Analysis of tissue samples at various developmental stages suggests that α-/β-TBECH was metabolized rapidly, and thus is unlikely to cause any direct, long-term effects on the development of zebra finch embryos or offspring. |
| Databáze: | OpenAIRE |
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