Enantioselective Synthesis of the Fully Functionalized ABC Ring of Zoanthenol

Autor:	Naoki Sugano, Masahiro Hirama, Shuji Yamashita, Shoji Kobayashi, Yuuki Koizumi, Go Hirai, Hiroki Oguri
Rok vydání:	2008
Předmět:	Molecular Structure Chemistry Stereochemistry Zoanthenol Organic Chemistry Enantioselective synthesis Total synthesis Stereoisomerism Oxidation reduction General Chemistry Ring (chemistry) Key features Biochemistry Heterocyclic Compounds Bridged-Ring Alkaloids Molecule Oxidation-Reduction
Zdroj:	Chemistry - An Asian Journal. 3:1549-1557
ISSN:	1861-471X 1861-4728
DOI:	10.1002/asia.200800079
Popis:	Zoanthenol, isolated from Zoanthus sp., possesses an extremely complex architecture including contiguous quaternary carbons. An enantioselective synthesis of the fully functionalized ABC-ring of zoanthenol has been achieved and is described herein. The key features of the synthesis are the enzymatic kinetic optical resolution and the Mizoroki-Heck/Simmons-Smith reaction strategy used to construct the congested asymmetric quaternary carbons.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d1a198a25cbfe96a5d25a5bafc2452 https://doi.org/10.1002/asia.200800079 Zobrazit plný text záznamu Plný text