Association between Three Low-Carbohydrate Diet Scores and Lipid Metabolism among Chinese Adults

Autor: Li-Juan Tan, Sangah Shin, Seong-Ah Kim
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
0301 basic medicine
dietary factor
Physiology
Blood lipids
030204 cardiovascular system & hematology
Diet
Carbohydrate-Restricted
Eating
chemistry.chemical_compound
0302 clinical medicine
animal based
Medicine
Nutritional Physiological Phenomena
Gonadal Steroid Hormones
Aged
80 and over
Hypertriglyceridemia
Sex Characteristics
Nutrition and Dietetics
plant based
Confounding
Middle Aged
Quartile
Research Design
Chinese adults
Female
lipids (amino acids
peptides
and proteins)
lcsh:Nutrition. Foods and food supply
Adult
CHNS
Hypercholesterolemia
lcsh:TX341-641
Article
LCD score
Young Adult
03 medical and health sciences
Sex Factors
Asian People
Humans
Aged
030109 nutrition & dietetics
Triglyceride
business.industry
dyslipidemia
nutritional and metabolic diseases
Odds ratio
Lipid Metabolism
medicine.disease
Dietary Fats
Confidence interval
chemistry
business
Dyslipidemia
Food Science
Zdroj: Nutrients
Volume 12
Issue 5
Nutrients, Vol 12, Iss 1307, p 1307 (2020)
ISSN: 2072-6643
DOI: 10.3390/nu12051307
Popis: This study investigated the blood lipid levels of 5921 Chinese adults aged >
18 years using data from the China Health and Nutrition Survey 2009. Diet information was collected through 3 day, 24 h recalls by trained professionals. The low-carbohydrate diet (LCD) score was determined according to the percentage of energy obtained from carbohydrate, protein, and fat consumption. Dyslipidemia was defined when one or more of the following abnormal lipid levels were observed: high cholesterol levels, high triglyceride levels, and low high-density lipoprotein cholesterol levels. Multivariate adjusted odds ratios (ORs) and their 95% confidence intervals (95% CIs) were calculated using logistic regression models. After adjusting the confounding variables, in males, the OR of hypercholesterolemia was 1.87 (95% CI, 1.23&ndash
2.85
p for trend = 0.0017) and the OR of hypertriglyceridemia was 1.47 (95% CI, 1.04&ndash
2.06
p for trend = 0.0336), on comparing the highest and lowest quartiles of the LCD score. The animal-based LCD score showed a similar trend. The OR of hypercholesterolemia was 2.15 (95% CI, 1.41&ndash
3.29
p for trend = 0.0006) and the OR of hypertriglyceridemia was 1.51 (95% CI, 1.09&ndash
2.10
p for trend = 0.0156). However, there was no significant difference between plant-based LCD scores and dyslipidemia. In females, lipid profiles did not differ much among the quartiles of LCD scores&mdash
only the animal-based LCD score was statistically significant with hypercholesterolemia. The OR of hypercholesterolemia was 1.64 (95% CI, 1.06&ndash
2.55), on comparing the highest and lowest quartiles of the LCD score. In conclusion, a higher LCD score, indicating lower carbohydrate intake and higher fat intake, especially animal-based fat, was significantly associated with higher odds of hypercholesterolemia and hypertriglyceridemia in Chinese males. Future studies investigating the potential mechanisms by which macronutrient types and sex hormones affect lipid metabolism are required.
Databáze: OpenAIRE
Externí odkaz: