A decade of trends in the distribution and antimicrobial susceptibility of prevalent uropathogens among pediatric patients from Tehran, Iran during 2005-2016
| Autor: | Alireza Nateghian, Sina Karaji, Khosrow Zamani |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Imipenem Urinary tract infection medicine.drug_class business.industry Antibiotics 030232 urology & nephrology Ceftazidime Asian Focus Antimicrobial resistance Diseases of the genitourinary system. Urology Ciprofloxacin 03 medical and health sciences 0302 clinical medicine Antibiotic resistance Nitrofurantoin Amikacin 030220 oncology & carcinogenesis Internal medicine medicine Pediatric hospital Gentamicin RC870-923 business medicine.drug |
| Zdroj: | Asian Journal of Urology Asian Journal of Urology, Vol 8, Iss 3, Pp 253-259 (2021) |
| ISSN: | 2214-3882 |
| Popis: | Objectives: To determine changes in the distribution of uropathogens and their antimicrobial resistance in pediatric patients in a children's hospital from 2005 to 2016. Methods: A cross-sectional analysis of uropathogens and their antimicrobial resistance within inpatient children was performed over the 11-year period, 2005 to 2016, in Ali Asghar children's hospital. The rate of antibiotic resistance among patients was evaluated according to demographic data including age, sex, urinary tract abnormities and history of antibiotic consumption. Results: In total, 958 female and 349 male positive cultures were analyzed. Escherichia coli (E. coli) (77.6%) was the most common causative agent of urinary tract infection (UTI) in children and Klebsiella pneumoniae (10.4%), Pseudomonas aeruginosa (2.4%), and Enterococcus spp (2.4%) were less frequent isolated bacteria. The resistance rates of E. coli isolates were increased against amikacin, ceftriaxone, ceftazidime, ciprofloxacin, cotrimoxazole and imipenem from 2005 to 2010. However, we observed a decreasing trend for some of antibiotics including amikacin, gentamicin, imipenem, ceftazidime and cotrimoxazole during 2014–2016. The rate of antibiotic resistance was greater in boys than in girls against many antibiotics. The rate of resistance to amikacin, gentamicin, nitrofurantoin and cotrimoxazole in patients aged |
| Databáze: | OpenAIRE |
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