Bone Scan Alterations in Aromatase Inhibitor–Treated Patients
| Autor: | Eveline De Cuypere, Annick Van den Bruel, Frank De Geeter, Michel Langlois |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Oncology medicine.medical_specialty medicine.drug_class medicine.medical_treatment Antineoplastic Agents Breast Neoplasms Bone scans Bone and Bones Breast cancer Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Aromatase Radionuclide Imaging skin and connective tissue diseases Aromatase inhibitor biology Aromatase Inhibitors business.industry General Medicine Middle Aged medicine.disease biology.protein Female business Adjuvant Hormone |
| Zdroj: | Clinical Nuclear Medicine. 40:38-40 |
| ISSN: | 0363-9762 |
| DOI: | 10.1097/rlu.0000000000000588 |
| Popis: | We report bone scan changes in 3 patients receiving aromatase inhibitors as adjuvant treatment for postmenopausal hormone receptor-positive breast cancer. Compared with bone scans before treatment, repeated scans after at least 10 months of aromatase inhibitor treatment showed increased activity in the peripheral skeleton and the skull. In 2 patients, these alterations could be correlated with increased markers of bone turnover. They probably result from high bone turnover induced by estrogen depletion caused by aromatase inhibitors. This effect should be taken into account in the differential diagnosis of a bone scan pattern suggestive of hyperparathyroidism, which was ruled out. |
| Databáze: | OpenAIRE |
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