From Inflammation to Current and Alternative Therapies Involved in Wound Healing

Autor: Marilene Oliveira da Rocha Borges, Mariana Barreto Serra, Antonio Carlos Romão Borges, Selma do Nascimento Silva, Iracelle Carvalho Abreu, Wermerson Assunção Barroso, Neemias Neves da Silva
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: International Journal of Inflammation, Vol 2017 (2017)
International Journal of Inflammation
ISSN: 2042-0099
2090-8040
Popis: Wound healing is a complex event that develops in three overlapping phases: inflammatory, proliferative, and remodeling. These phases are distinct in function and histological characteristics. However, they depend on the interaction of cytokines, growth factors, chemokines, and chemical mediators from cells to perform regulatory events. In this article, we will review the pathway in the skin healing cascade, relating the major chemical inflammatory mediators, cellular and molecular, as well as demonstrating the local and systemic factors that interfere in healing and disorders associated with tissue repair deficiency. Finally, we will discuss the current therapeutic interventions in the wounds treatment, and the alternative therapies used as promising results in the development of new products with healing potential.
Databáze: OpenAIRE
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