Autor: |
F. S. Hill, Tracy Chui-hsu Yang, K. George, Marco Durante, S. W. Oram, Wen Deng, J. N. Lucas, C. L. Owens, Honglu Wu |
Přispěvatelé: |
J. N., Luca, W., Deng, S. W., Oram, F. S., Hill, Durante, Marco, K., George, H., Wu, C. L., Owen, T., Yang |
Rok vydání: |
1999 |
Předmět: |
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Zdroj: |
Radiation Research. 151:85 |
ISSN: |
0033-7587 |
DOI: |
10.2307/3579752 |
Popis: |
In the present study, F ratios for both stable chromosome aberrations, i.e. ratios of translocations to pericentric inversions, and unstable aberrations, i.e. dicentrics and centric rings, were measured using fluorescence in situ hybridization. F ratios for stable aberrations measured after exposure to low (2.89 Gy 60Co gamma rays) and high-LET (0.25 Gy 56Fe ions; 1.25 Gy 56Fe ions; 3.0 Gy 12C ions) radiation were 6.5 +/- 1.5, 4.7 +/- 1.6, 9.3 +/- 2.5 and 10.4 +/- 3.0, respectively. F ratios for unstable aberrations measured after low (2.89 Gy 60Co gamma rays) and high-LET (0.25 Gy 56Fe ions; 3.0 Gy 12C ions) radiations were 6.5 +/- 1.6, 6.3 +/- 2.3 and 11.1 +/- 3.7, respectively. No significant difference between the F ratios for low- and high-LET radiation was found. Further tests on the models for calculation of the F ratio proposed by Brenner and Sachs (Radiat. Res. 140, 134-142, 1994) showed that the F ratio may not be straightforward as a practical fingerprint for densely ionizing radiation. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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