Long-term reno-cardiovascular effects of orally administered aconiti tuber in humans
| Autor: | Shu-Ling Liu, Ho-Chan Chen, Shu-Shi Chang, Ming-Tsuen Hsieh |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Chronotropic
Inotrope Adult Male medicine.medical_specialty Vasodilator Agents Renal function Hemodynamics Kidney Cardiovascular System Cardiovascular Physiological Phenomena Oral administration Internal medicine medicine Humans Adverse effect business.industry General Medicine Endocrinology medicine.anatomical_structure Complementary and alternative medicine Renal blood flow business Drugs Chinese Herbal |
| Zdroj: | The American journal of Chinese medicine. 18(1-2) |
| ISSN: | 0192-415X |
| Popis: | The reno-cardiovascular effects of Aconiti Tuber were studied. In a controlled, double-blind, and randomized clinical trial, it was found that in 9 months, Aconiti Tuber, after preparation (120°C, 40 min), (1) had no apparent adverse effects, (2) showed positive inotropic, postive chronotropic, and vasodilator effects, (3) increased renal blood flow, and glomerular filtration rate, Na+/CI-/K+ excretions. The renal function test results could be interpreted as secondary to hemodynamic changes. We conclude that specially prepared Aconiti Tuber may be a promising cardiotonic agent. |
| Databáze: | OpenAIRE |
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