Sero-Prevalence of Bloodborne Tumor Viruses (HCV, HBV, HTLV-I and KSHV Infections) and Related Risk Factors among Prisoners in Razavi Khorasan Province, Iran, in 2008
| Autor: | Fateme Homaei Shandiz, Mohsen Seyed Nozadi, Seyed Moayed Alavian, Rosita Vakili, Seyed Mohammad Jazayeri, Narges Valizade, Mohammad Khajedaluee, Ali Babaei, Tahereh Hassannia |
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| Rok vydání: | 2016 |
| Předmět: |
HBsAg
Veterinary medicine medicine.medical_specialty Epidemiology viruses Population Human T-Cell Leukemia Virus Type I (HTLV-I) 03 medical and health sciences 0302 clinical medicine Tumor Virus Medicine 030212 general & internal medicine education education.field_of_study Hepatology biology Hepatitis C Virus (HCV) Transmission (medicine) business.industry Prison virus diseases Virology Kaposi’s Sarcoma-Associated Herpes Virus (KSHV) digestive system diseases Sero prevalence Hepatitis B Virus (HBV) Kowsar Infectious Diseases biology.protein 030211 gastroenterology & hepatology Antibody business Research Article |
| Zdroj: | Hepatitis Monthly |
| ISSN: | 1735-3408 1735-143X |
| DOI: | 10.5812/hepatmon.31541 |
| Popis: | Background Prisoners are at high risk of blood borne and sexually transmitted infections due to their high involvement in risky behaviors. In this descriptive/cross-sectional study, the prevalence, sero-prevalence, and risk factors for bloodborne tumor viruses including HTLV-I, HBV, HCV, and KSHV were evaluated among inmates of two central prisons in the northeast of Iran. Methods Blood samples of 1114 inmates were analyzed for the presence of anti HTLV-I, KSHV, and HCV antibodies and HBsAg by ELISA. PCR tests were performed to confirm the presence of these viruses in plasma and identify the current infections. Results The sero-prevalence of HCV, HBV, HTLV-I, and KSHV was 24.5%, 4.2%, 3.4%, and 3.2% and the prevalence of HCV, HBV, HTLV-I, and KSHV was 19.1%, 2.1%, 2%, and 3%, respectively. HCV infection was significantly associated with history of imprisonment, tobacco consumption, alcohol consumption, intravenous drug use, length of imprisonment, and type of crime committed. Thirty one (2.8%) prisoners had HCV-KSHV co-infection, 16 (1.5%) had HCV-HTLV-I co-infection, and 14 (1.3%) had HBV-HCV co-infection. Triple co-infection was observed in seven cases and one case had four infections concomitantly. Conclusions This epidemiological study indicated different rates and transmission risks for these viruses. HCV was the most contagious viral infection and HTLV-I was the weakest in the prisoners. Apart from KSHV infection which its prevalence was as twice as in the general population, the prevalence of HBV and HTLV-I in prisoners was nearly in ranges of the general population. |
| Databáze: | OpenAIRE |
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