The variability and dietary dependence of urinary oxalate excretion in recurrent calcium stone formers
| Autor: | G Stratmann, Jennifer M. Brown, B M Mottram, A H Chalmers, David Cowley |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Adult
Male 030213 general clinical medicine medicine.medical_specialty Urinary system Clinical Biochemistry Oxalic acid chemistry.chemical_element 030209 endocrinology & metabolism Calcium Oxalate Excretion 03 medical and health sciences chemistry.chemical_compound Kidney Calculi 0302 clinical medicine Recurrence Internal medicine medicine Humans Aged Kidney Oxalates Chemistry Oxalic Acid General Medicine Middle Aged Urinary calcium Diet Calcium Dietary Endocrinology medicine.anatomical_structure Oxalate Measurement Female |
| Zdroj: | Europe PubMed Central ResearcherID |
| ISSN: | 0004-5632 |
| Popis: | Twenty-two recurrent calcium stone formers had 24-h urinary oxalate excretions on their home diets which were significantly greater than those of 30 normal subjects (0·48±0·23 mmol/d; mean±SD compared with 0·31±0·11; P On a hospital diet containing 1000 mg calcium per day, urinary oxalate excretion fell significantly from 0·48±0·23 mmol/d to 0·32±0·12; P All patients had recurrent symptomatic stone disease and had been advised to avoid foods rich in oxalate. Whilst poor compliance is a possible explanation for the variability in oxalate excretion, we believe it is more likely that there is an inadvertent intake of oxalogenic precursors in their diet. As normal subjects do not demonstrate hyperoxaluria on similar home diets, stone formers may have a metabolic defect in the handling of these precursors. |
| Databáze: | OpenAIRE |
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