Effects of intermittent hypoxia-hyperoxia on mobility and perceived health in geriatric patients performing a multimodal training intervention: a randomized controlled trial

Autor: Martin Burtscher, Rudolf Likar, Ulrike Bayer, Stefan Neuwersch, Brigitte Trummer, Oleg S. Glazachev, Susanne Demschar, Georg Pinter, Haro Stettner
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
medicine.medical_specialty
Visual analogue scale
medicine.medical_treatment
Health Status
Intervention
lcsh:Geriatrics
Hyperoxia
law.invention
03 medical and health sciences
0302 clinical medicine
Elderly
Randomized controlled trial
Double-Blind Method
law
medicine
Humans
030212 general & internal medicine
Effects of sleep deprivation on cognitive performance
Range of Motion
Articular
Hypoxia
Exercise
Postural Balance
Aged
Aged
80 and over
Perceived health
Rehabilitation
Exercise Tolerance
business.industry
Tinetti test
Intermittent hypoxia
Hypoxia (medical)
Middle Aged
Multimodal training
Exercise Therapy
Clinical trial
lcsh:RC952-954.6
Time and Motion Studies
Physical therapy
Female
Geriatrics and Gerontology
medicine.symptom
business
human activities
030217 neurology & neurosurgery
Research Article
Zdroj: BMC Geriatrics
BMC Geriatrics, Vol 19, Iss 1, Pp 1-9 (2019)
ISSN: 1471-2318
Popis: Background Additional benefits of passive exposures to intermittent hypoxia and hyperoxia on cognitive performance and functional exercise capacity have been demonstrated in geriatric patients who performed a multimodal training program. The main goal of the present study was to evaluate effects of adding intermittent hypoxic-hyperoxic training (IHHT) to a multimodal training intervention (MTI) on mobility and perceived health in old individuals at a Geriatric Day Hospital. Methods Thirty-four patients between 64 and 92 years participated in the double blind, randomized and controlled clinical trial. The elderly patients attended in a 5–7 weeks lasting MTI (strength, endurance, balance, reaction, flexibility, coordination, and cognitive exercises) and performed IHHT (breathing 10–14% oxygen for 4–7 min followed by 2–4 min 30–40% oxygen) in the Hypoxic Group (HG) or placebo treatment with ambient air in the Normoxic Group (NG) in parallel. Before and after all treatments, mobility was assessed by the Tinetti Mobility Test (TMT), the Timed-Up-and-Go Test (TUG) and Barthel-Index, while perceived health was assessed by one part of the EQ-5D Test, the EQ visual analogue scale (EQ VAS). Results After the MTI plus IHHT or normoxia sessions, results of the TMT, TUG, Barthel Index and EQ-VAS revealed no significant difference between HG and NG (+ 14.9% vs + 15.4%, p = 0.25; − 21% vs − 26.3%, p = 0.51; + 4.2% vs + 3.6%, p = 0.56; + 37.9% vs + 33.9%, p = 0.24;). Conclusions IHHT added to MTI did not elicit additional improvements in perceived health and mobility compared to MTI alone.
Databáze: OpenAIRE
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