Acceptability, effectiveness and safety of a Renew ® anal insert in patients who have undergone restorative proctocolectomy with ileal pouch–anal anastomosis
| Autor: | J. D. Hodgkinson, E. Bradshaw, C. A. Leo, Carolynne J. Vaizey, Emanuel Cavazzoni, Phillip Lung, Jonathan Segal, R. Ilangovan, O D Faiz, Susan K. Clark, Ailsa Hart |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
IMPACT faecal incontinence medicine.medical_treatment DEVICE ® Familial adenomatous polyposis 03 medical and health sciences 0302 clinical medicine FECAL INCONTINENCE Renew((R)) Anopress medicine Fecal incontinence In patient Prospective cohort study Anopress Science & Technology Cancer prevention Gastroenterology & Hepatology ileoanal pouch IPAA Renew business.industry Proctocolectomy Gastroenterology 1103 Clinical Sciences medicine.disease Ulcerative colitis Surgery Ileal Pouch Anal Anastomosis Renew® Anopress 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology medicine.symptom business Life Sciences & Biomedicine |
| Zdroj: | Colorectal Disease. 21:73-78 |
| ISSN: | 1463-1318 1462-8910 |
| Popis: | Introduction Restorative proctocolectomy has gained acceptance in the surgical management of medically refractive ulcerative colitis and cancer prevention in familial adenomatous polyposis. Incontinence following restorative proctocolectomy occurs in up to 25% of patients overnight. The Renew® insert is an inert single-use device which acts as an anal plug. The aim of this study was to assess the acceptability, effectiveness and safety of the Renew® insert in patients who have undergone restorative proctocolectomy. The device has yet to be assessed in patients who have undergone restorative proctocolectomy. Method This was a prospective study exploring the acceptability, effectiveness and safety of the Renew® insert in improving incontinence in patients who had undergone restorative proctocolectomy. A total of 15 patients with incontinence were asked to use the Renew® insert for 14 days following their standard care. The Incontinence Questionnaire-Bowels was used pre- and posttreatment to assess response and patients were asked to report the perceived acceptability, effectiveness and safety of the device at the end of the trial. Results The device was acceptable to 8/15 (53%) of patients and was effective in 6/15 (40%). Only 2/15 (13%) of patients raised any safety concerns, and these were minor. The device was associated with a significant reduction in night seepage (P = 0.034). Conclusion In a small study, the Renew® insert can be both acceptable and effective and is also associated with few safety concerns. It is also associated with significant reductions in night-time seepage. |
| Databáze: | OpenAIRE |
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