Volatile anaesthetics and cardiac protection in abdominal surgery

Autor: Jasminka Kopić
Rok vydání: 2015
Předmět:
Zdroj: Wiener klinische Wochenschrift. 127:543-548
ISSN: 1613-7671
0043-5325
DOI: 10.1007/s00508-015-0819-2
Popis: Clinical studies have shown that sevoflurane is cardio-protective in cardiac surgery patients, but this effect is doubtful in general surgery patients. This study has researched the influence of sevoflurane on the perioperative cardiac function and the incidence of cardiac ischaemic events in abdominal surgical patients. Out of 80 patients scheduled for elective colorectal surgery, 42 received balanced sevoflurane-fentanyl anaesthesia, while 38 received intravenous midazolam-fentanyl anaesthesia. The cardiac index (CI) and cardiac function index (CFI) were measured by the PiCCO device, and Troponin I levels were measured at the beginning of surgery, as well as 4, 12 and 24 h afterwards. BNP was measured at the beginning of surgery, and 24 h afterwards. The data analysis was conducted using the Mann–Whitney nonparametric test, with statistical significance set at p
Databáze: OpenAIRE