Use of 5-Fluorouracil for Management of the Thick-Skinned Nose
Autor: | Leslie E. Irvine, Paul S. Nassif |
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Rok vydání: | 2018 |
Předmět: |
Adult
Male medicine.medical_specialty Esthetics Injections Intradermal medicine.medical_treatment Scar tissue Injections Intralesional 030230 surgery Risk Assessment Rhinoplasty Cohort Studies Cicatrix 030207 dermatology & venereal diseases 03 medical and health sciences Postoperative Complications 0302 clinical medicine Preoperative Care medicine Humans Nose Volume concentration Retrospective Studies Skin Postoperative Care business.industry Soft tissue Single injection Middle Aged Surgery Treatment Outcome medicine.anatomical_structure Fluorouracil Female Beak formation business Follow-Up Studies medicine.drug |
Zdroj: | Facial Plastic Surgery. 34:009-013 |
ISSN: | 1098-8793 0736-6825 |
DOI: | 10.1055/s-0037-1617420 |
Popis: | Patients with a thick nasal skin and soft tissue envelope can have unpredictable results and irregular scarring after rhinoplasty surgery. These patients typically have sebaceous tissue over the nasal tip and are particularly susceptible to soft tissue polly beak formation and excess scar tissue in the radix, tip, and septum. Targeted injections of 5-fluorouracil alone or mixed with low concentrations of steroid can be useful to prevent and treat excess postoperative scar tissue deposition. Ideally, four to six injections are performed every 1 to 4 weeks beginning 1 week postoperatively. The injections are most beneficial when performed within the first 3 months after surgery. Even a single injection may improve outcomes with minimal side effects. |
Databáze: | OpenAIRE |
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