Phylogenetics and the Human Microbiome
| Autor: | Frederick A. Matsen |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
0106 biological sciences
16S phylogenetic methods Computational biology Biology microbial ecology 010603 evolutionary biology 01 natural sciences metagenome 03 medical and health sciences Phylogenetics RNA Ribosomal 16S Genetics Humans Quantitative Biology - Genomics Microbiome Quantitative Biology - Populations and Evolution human microbiota Phylogeny Ecology Evolution Behavior and Systematics 030304 developmental biology Genomics (q-bio.GN) 0303 health sciences Bacteria Ecology Microbiota Populations and Evolution (q-bio.PE) Human microbiome human microbiome Metagenomics FOS: Biological sciences Earth Microbiome Project Special Issue: Mathematical and Computational Evolutionary Biology (2013) |
| Zdroj: | Systematic Biology |
| ISSN: | 1076-836X 1063-5157 |
| DOI: | 10.1093/sysbio/syu053 |
| Popis: | The human microbiome is the ensemble of genes in the microbes that live inside and on the surface of humans. Because microbial sequencing information is now much easier to come by than phenotypic information, there has been an explosion of sequencing and genetic analysis of microbiome samples. Much of the analytical work for these sequences involves phylogenetics, at least indirectly, but methodology has developed in a somewhat different direction than for other applications of phylogenetics. In this paper I review the field and its methods from the perspective of a phylogeneticist, as well as describing current challenges for phylogenetics coming from this type of work. Comment: to appear in Systematic Biology |
| Databáze: | OpenAIRE |
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