GW25-e1666 The knockdown of the HDAC1 gene promotes the directed differentiation of bone mesenchymal stem cells into cardiomyocytes
| Autor: | Lu Dongfeng, Xiao-wen Xing, Zhao-hua Zeng, Dong-feng Lu, Zi-zhuo Su, Ying Wang, Zhi-yu He |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Gene knockdown
animal structures business.industry Mesenchymal stem cell hemic and immune systems Phenotype HDAC1 Cell biology Viral vector enzymes and coenzymes (carbohydrates) Directed differentiation stomatognathic system embryonic structures Medicine Cardiology and Cardiovascular Medicine business Gene |
| Zdroj: | Journal of the American College of Cardiology. 64:C51-C52 |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/j.jacc.2014.06.250 |
| Popis: | The objective of this study was to conduct a preliminary exploration of the role of the histone deacetylase 1 (HDAC1) gene in the phenotypic differentiation of rat bone mesenchymal stem cells (BMSCs) into cardiomyocytes by transfecting BMSCs with an HDAC1-RNAi lentiviral vector and thereby |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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