Long-standing type II diabetes mellitus is not a risk factor for slow gastric emptying in critically ill patients
| Autor: | Ross N. Butler, Nam Q. Nguyen, Richard H. Holloway, Geoffrey P. Davidson, Marianne J. Chapman, Betty Zacharakis, Laura K. Bryant, Robert J. Fraser, Marc A Ritz |
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| Přispěvatelé: | Nguyen, Nam, Chapman, Marianne, Fraser, R, Ritz, Marc, Bryant, L, Butler, Ross Norman, Davidson, Geoffrey, Zacharakis, B, Holloway, R |
| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty critically ill Critical Illness Clinical Sciences Gastric emptying Type 2 diabetes Critical Care and Intensive Care Medicine Gastroenterology Risk Factors Internal medicine Intensive care Diabetes mellitus medicine Humans Risk factor APACHE Retrospective Studies Breath test Chi-Square Distribution medicine.diagnostic_test APACHE II business.industry breath test Stomach Middle Aged medicine.disease Respiration Artificial medicine.anatomical_structure Endocrinology Breath Tests Diabetes Mellitus Type 2 Gastric Emptying Case-Control Studies diabetes mellitus Female business |
| Zdroj: | Intensive Care Medicine. 32:1365-1370 |
| ISSN: | 1432-1238 0342-4642 |
| Popis: | Delayed gastric emptying (GE) is common both in critical illness and in patients with diabetes mellitus (DM). The effect of DM on the incidence of slow GE in these patients is unknown. We evaluated the effect of DM on liquid GE in critically ill patients. Retrospective analysis of GE using a standard [13C]octanoic acid breath test in 12 type 2 DM patients compared with (a) 44 critically ill patients without DM, including (b) a subgroup of 15 age- and sex-matched patients and (c) 15 healthy volunteers. We determined the gastric emptying coefficient (GEC) and the gastric half-emptying time (t 50). Mean APACHE II scores, blood glucose levels and use of morphine were similar between patient groups. GE was faster in critically ill patients with DM (t 50 122 ± 11 min, GEC: 3.8 ± 0.3) than in patients without DM (t 50 168 ± 16 min, GEC 2.8 ± 0.1) and in age- and sex-matched controls (t 50 165 ± 13 min, GEC 2.7 ± 0.2) and was similar to that in healthy volunteers (t 50 148 ± 13 min, GEC 3.5 ± 0.1). The proportion of patients with slow emptying (GEC |
| Databáze: | OpenAIRE |
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