Weight loss after bariatric surgery in obese adolescents: a systematic review and meta-analysis
| Autor: | Federico Angriman, Manuel Castillo-Angeles, Julie E. Goodman, Alessandra Storino, Atsushi Endo, Felipe E. Pedroso, Ricardo Castillo, Hormuzdiyar H. Dasenbrock, Ammara A. Watkins, Jeffrey L. Zitsman |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Pediatric Obesity medicine.medical_specialty Adolescent Gastric bypass Bariatric Surgery 030209 endocrinology & metabolism 03 medical and health sciences 0302 clinical medicine Weight loss Weight Loss medicine Humans Gastric sleeve 030212 general & internal medicine Young adult Child Postoperative Care business.industry medicine.disease Obesity Confidence interval Surgery Treatment Outcome Meta-analysis Female medicine.symptom Epidemiologic Methods business Body mass index |
| Zdroj: | Surgery for Obesity and Related Diseases. 14:413-422 |
| ISSN: | 1550-7289 |
| DOI: | 10.1016/j.soard.2017.10.003 |
| Popis: | Of adolescents in the United States, 20% have obesity and current treatment options prioritize intensive lifestyle interventions that are largely ineffective. Bariatric surgery is increasingly being offered to obese adolescent patients; however, large-scale effectiveness data is lacking. We used MEDLINE, Embase, and Cochrane databases, and a manual search of references to conduct a systematic review and meta-analysis on overall weight loss after gastric band, gastric sleeve, and gastric bypass in obese adolescent patients (age ≤19) and young adults (age ≤21) in separate analyses. We provided estimates of absolute change in body mass index (BMI, kg/m2) and percent excess weight loss across 4 postoperative time points (6, 12, 24, and 36 mo) for each surgical subgroup. Study quality was assessed using a 10 category scoring system. Data were extracted from 24 studies with 4 having multiple surgical subgroups (1 with 3, and 3 with 2 subgroups), totaling 29 surgical subgroup populations (gastric band: 16, gastric sleeve: 5, gastric bypass: 8), and 1928 patients (gastric band: 1010, gastric sleeve: 139, gastric bypass: 779). Mean preoperative BMI (kg/m2) was 45.5 (95% confidence interval [CI]: 44.7, 46.3) in gastric band, 48.8 (95%CI: 44.9, 52.8) in gastric sleeve, and 53.3 (95%CI: 50.2, 56.4) in gastric bypass patients. The short-term weight loss, measured as mean (95%CI) absolute change in BMI (kg/m2) at 6 months, was -5.4 (-3.0, -7.8) after gastric band, -11.5 (-8.8, -14.2) after gastric sleeve, and -18.8 (-10.9, -26.6) after gastric bypass. Weight loss at 36 months, measured as mean (95%CI) absolute change in BMI (kg/m2) was -10.3 (-7.0, -13.7) after gastric band, -13.0 (-11.0, -15.0) after gastric sleeve, and -15.0 (-13.5, -16.5) after gastric bypass. Bariatric surgery in obese adolescent patients is effective in achieving short-term and sustained weight loss at 36 months; however, long-term data remains necessary to better understand its long-term efficacy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|