Symptomatic cytomegalovirus (CMV) infections identified by image cytometry and other parameters for CMV infection
| Autor: | W. T. Dorp, E. Jonges, N. M. Jiwa, G. W. Gemert, L. A. Es, J. S. Ploem, T. H. The, F. J. Woude |
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| Rok vydání: | 1990 |
| Předmět: |
Nephrology
medicine.medical_specialty Allergy Congenital cytomegalovirus infection Cytomegalovirus Fluorescent Antibody Technique Urine Buffy coat Antibodies Viral Immediate-Early Proteins Postoperative Complications Antigen Internal medicine mental disorders Image Processing Computer-Assisted medicine Humans Antigens Viral Transplantation Hematology business.industry virus diseases medicine.disease Immunohistochemistry Kidney Transplantation Cytomegalovirus Infections Immunology business psychological phenomena and processes |
| Zdroj: | Transplant International. 3:212-216 |
| ISSN: | 1432-2277 0934-0874 |
| DOI: | 10.1111/j.1432-2277.1990.tb01926.x |
| Popis: | Thirty-eight renal transplant recipients were followed during the first 3 months after transplantation. Once weekly, cultures of urine and buffy coat for cytomegalovirus (CMV) were taken and an immunocytochemical assay for immediate early antigens of CMV (IEA assay) was performed. Thirty patients had evidence of a CMV infection and 11 had a symptomatic CMV infection. All symptomatic patients had one or more positive urine cultures or a positive IEA assay. However, 15 patients with positive urine cultures and 12 patients with a positive IEA assay lacked any signs of symptomatic CMV disease. Moreover, 6 out of 15 patients with positive buffy coat cultures for CMV did not have symptomatic CMV disease. Using a computerized system to quantify IEA-positive granulocytes, we show that the absolute number of positive cells per million correlates very well with the occurrence of symptomatic CMV disease. |
| Databáze: | OpenAIRE |
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