Biohumoral Indicators Influenced by Physical Activity in the Elderly
| Autor: | Guglielmo Torre, Paolo Borrione, Arrigo Giombini, Federica Fagnani, Maurizio Casasco, Fabio Pigozzi, Attilio Parisi, Matteo Turchetta, Erika Albo, Chiara Fossati |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
hypertension
noncommunicable diseases Scopus Physical activity MEDLINE physical activity lcsh:Medicine Review 030204 cardiovascular system & hematology Bioinformatics elderly 03 medical and health sciences 0302 clinical medicine Diabetes mellitus Medicine Elderly people 030212 general & internal medicine Metabolic biomarkers medicine.diagnostic_test diabetes business.industry lcsh:R biomarkers General Medicine medicine.disease Narrative review business Lipid profile |
| Zdroj: | Journal of Clinical Medicine, Vol 9, Iss 1115, p 1115 (2020) Journal of Clinical Medicine |
| ISSN: | 2077-0383 |
| Popis: | In the scientific landscape, there is a growing interest in defining the role of several biomolecules and humoral indicators of the aging process and in the modifications of these biomarkers induced by physical activity and exercise. The main aim of the present narrative review is to collect the available evidence on the biohumoral indicators that could be modified by physical activity (PA) in the elderly. Online databases including Pubmed, Web of science (Medline), and Scopus were searched for relevant articles published in the last five years in English. Keywords and combination of these used for the search were the following: “biological”, “indicators”, “markers”, “physical”, “activity”, and “elderly”. Thirty-four papers were analyzed for inclusion. Twenty-nine studies were included and divided into four categories: cardiovascular (CV) biomarkers, metabolic biomarkers, inflammatory markers-oxidative stress molecules, and other markers. There are many distinct biomarkers influenced by PA in the elderly, with promising results concerning the metabolic and CV indexes, as a growing number of studies demonstrate the role of PA on improving parameters related to heart function and CV risk like atherogenic lipid profile. Furthermore, it is also a verified hypothesis that PA is able to modify the inflammatory status of the subject by decreasing the levels of pro-inflammatory cytokines, including interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α). PA seems also to be able to have a direct effect on the immune system. There is a strong evidence of a positive effect of PA on the health of elderly people that could be evidenced and “quantified” by the modifications of the levels of several biohumoral indicators. |
| Databáze: | OpenAIRE |
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