Predictors of hospitalization for COVID-19 in patients with autoimmune rheumatic diseases: results from a community cohort follow-up

Autor: Manuel F. Ugarte-Gil, Graciela S. Alarcón, Victor R. Pimentel-Quiroz, Denisse Toledo-Neira, Francisco Zevallos-Miranda, Rocío V. Gamboa-Cárdenas, Silvia Barzola-Cerrón, Cristina Reátegui-Sokolova
Rok vydání: 2021
Předmět:
Zdroj: Clinical Rheumatology
ISSN: 1434-9949
0770-3198
DOI: 10.1007/s10067-021-05833-1
Popis: Objective The identification of risk factors for COVID-19 adverse course in autoimmune rheumatic diseases (ARDs) is of the utmost importance when approaching patient management; however, data are scarce in relation to the Latin American population. The objective of this study was to determine predictors of hospitalization for COVID-19 patients from an ARD community cohort. Methods A real setting longitudinal study (March to November 2020) in an ARD community cohort was carried out. Potential predictors of hospitalization for COVID-19 examined included (1) sociodemographic variables (age, gender, education, tobacco use, socioeconomic status, and co-inhabitants), (2) comorbidities, (3) time to COVID-19 diagnosis, and (4) ARD’s features: clinical (disease type, disease duration, activity), treatment [corticosteroids use/doses, use of synthetic DMARDs (cDMARDs, tsDMARDs, and bDMARDs)], treatment schedule and non-adherence, and the Multidimensional Health Assessment Questionnaire (MDHAQ). Univariable and multivariable regression analysis were conducted; OR and 95% CI (p
Databáze: OpenAIRE