Ethnic differences in stratum corneum functions between Chinese and Thai infants residing in Bangkok, Thailand
| Autor: | Tsutomu Fujimura, Diane Laohathai, Thamthiwat Nararatwanchai, Hisashi Tsujimura, Yoshinori Takema, Kyoko Shima, Pakhawadee Palungwachira, Takashi Kitahara, Mitsuyuki Hotta, Jetchawa Chanthothai, Yuki Miyauchi |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male Ethnic group Physiology Dermatology Ceramides 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Asian People Body Water Vascular Capacitance Stratum corneum Ethnicity Medicine Humans Skin care Transepidermal water loss business.industry Infant Thailand Water Loss Insensible 030104 developmental biology medicine.anatomical_structure Pediatrics Perinatology and Child Health Racial differences Female Epidermis business |
| Zdroj: | Pediatric dermatology. 35(1) |
| ISSN: | 1525-1470 |
| Popis: | Background/objectives Ethnic and racial differences in infant skin have not been well characterized. The purpose of this study was to establish whether there are ethnic differences and similarities in the stratum corneum (SC) functions of Thai and Chinese infants. Methods Healthy infants 6 to 24 months of age (N = 60; 30 Thai, 30 Chinese) who resided in Bangkok, Thailand, were enrolled. Transepidermal water loss (TEWL) and SC hydration (capacitance) on the thigh, buttock, and upper arm were measured. Ceramide content was determined in the SC on the upper arm. Results SC hydration was not remarkably different between the two ethnicities at any site measured, but TEWL was significantly higher in Chinese infants than in Thai infants at all sites. Hydration of the SC was not significantly correlated with age in either ethnicity. TEWL had significant but weak correlations with age on the thigh and upper arm in Thai infants. Ceramide content was significantly higher in Chinese SC than in Thai SC. No relationship between ceramide content and TEWL or hydration was observed in either ethnicity. Conclusion The significant differences in TEWL and ceramide contents between Chinese and Thai infant skin could prove useful in designing skin care and diapering products that are best suited for each ethnicity. |
| Databáze: | OpenAIRE |
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