Assembly of Cellulose Nanocrystal–Lysozyme Composite Films with Varied Lysozyme Morphology
| Autor: | Gustav Nyström, Qun Ren, Nico Kummer, Silvia Campioni |
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| Rok vydání: | 2020 |
| Předmět: |
Materials science
Polymers and Plastics Sonication Composite number Nanoparticle Bioengineering 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Biomaterials chemistry.chemical_compound chemistry Nanocrystal Chemical engineering Self-healing hydrogels Materials Chemistry Nanoparticles Muramidase Lysozyme Cellulose 0210 nano-technology Antibacterial activity |
| Zdroj: | Biomacromolecules. 21:5139-5147 |
| ISSN: | 1526-4602 1525-7797 |
| Popis: | In modern society, there is a constant need for developing reliable, sustainable, and cost-effective antibacterial materials. Here, we investigate the preparation of cellulose nanocrystal (CNC)-lysozyme composite films via the well-established method of evaporation-induced self-assembly. We consider the effects of lysozyme concentration and aggregation state (native lysozyme, lysozyme amyloid fibers, and sonicated lysozyme amyloid fibers) on suspension aggregation and film-forming ability. Although at higher lysozyme loading levels (ca. 10 wt %), composite films lost their characteristic chiral nematic structuring, these films demonstrated improved mechanical properties and antibacterial activity with respect to CNC-only films, regardless of lysozyme aggregation state. We anticipate that the results presented herein could also contribute to the preparation of other CNC-protein-based materials, including films, hydrogels, and aerogels, with improved mechanical performance and antibacterial activity. |
| Databáze: | OpenAIRE |
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