Neisseria meningitidis serogroup W-135 carriage among US travelers to the 2001 Hajj
| Autor: | Jalaa' Abdelwahab, Leonard W. Mayer, Marty Cetron, Corie A. Noble, Peter M. Dull, Robyn M. Kaiser, David S. Stephens, Gloria W. Ajello, Margaret Becker, Nancy E. Rosenstein, Gwen A. Barnett, Tanja Popovic, Anne M. Whitney, Claudio Tavares Sacchi, Susanna Schmink, Jennifer M. Dolan-Livengood |
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| Rok vydání: | 2004 |
| Předmět: |
Serotype
Adult Male Saudi Arabia medicine.disease_cause Meningococcal disease Islam Polymerase Chain Reaction Microbiology Neisseria meningitidis Serogroup W-135 Immunology and Allergy Medicine Humans Serotyping Aged Travel business.industry Transmission (medicine) Neisseria meningitidis Outbreak Middle Aged medicine.disease Virology United States Vaccination Meningococcal Infections Infectious Diseases Carriage Carrier State Pharynx Hajj Female business |
| Zdroj: | The Journal of infectious diseases. 191(1) |
| ISSN: | 0022-1899 |
| Popis: | In 2000, a large international outbreak of meningococcal disease caused by Neisseria meningitidis serogroup W-135 was identified among pilgrims returning from the Hajj in Saudi Arabia. To assess ongoing risk, we evaluated N. meningitidis carriage among US travelers to the 2001 Hajj. Of 25 N. meningitidis isolates obtained, 15 (60%) were nongroupable and 8 (32%) were serogroup W-135 when tested by standard slide-agglutination techniques. Two additional nongroupable isolates were characterized as serogroup W-135 when tested by polymerase chain reaction. Nine of 10 serogroup W-135 isolates were indistinguishable from the Hajj-2000 clone. None of the departing, but 9 (1.3%) of the returning, pilgrims carried serogroup W-135 (P=.01); all carriers reported previous vaccination. Carriage of N. meningitidis serogroup W-135 increased significantly in pilgrims returning from the Hajj. Although the risk of disease to pilgrims appears to be low, the risk of spread to others of this pathogenic strain remains a concern. |
| Databáze: | OpenAIRE |
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