Skeletal muscle metastasis with bone metaplasia from colon cancer: A case report and review of the literature
| Autor: | Zeyun Zhao, Jiannan Li, Donglin Li, Shuang Wang, Min Wang, Yu Guo, An Shang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Skeletal muscle metastasis
Pathology medicine.medical_specialty Tumor mutation burden Colorectal cancer Ossification business.industry Soft tissue metastasis Skeletal muscle General Medicine medicine.disease digestive system diseases Metastasis Colon cancer medicine.anatomical_structure Bone Metaplasia BRAF mutation Case report medicine medicine.symptom business |
| Zdroj: | World Journal of Clinical Cases |
| ISSN: | 2307-8960 |
| Popis: | BACKGROUND Colon cancer is a common malignant disease of the gastrointestinal tract and usually occurs at the junction of the rectum and sigmoid colon. Lymphatic and hematogenous metastases occur frequently in colon cancer and the most common metastatic sites include the liver, lung, peritoneum, bone, and lymph nodes. As a manifestation of advanced tumor spread and metastasis, soft tissue metastasis, especially skeletal muscle metastasis with bone metaplasia caused by colon cancer, is rare, accounting for less than 1% of metastases. CASE SUMMARY A 43-year-old male patient developed skeletal muscle metastasis with bone metaplasia of the right proximal thigh 5 mo after colon cancer was diagnosed. The patient was admitted to the hospital because of pain caused by a local mass on his right thigh. Positron emission tomography-computed tomography showed many enlarged lymph nodes around the abdominal aorta but no signs of lung or liver metastases. Color ultrasound revealed a mass located in the skeletal muscle and the results of histological biopsy revealed a poorly differentiated adenocarcinoma suspected to be distant metastases from colon cancer. Immunohistochemistry showed small woven bone components that were considered to be ossified. CONCLUSION This case reminds us that for patients with advanced colorectal tumors, we should be alert to the possibility of unconventional metastasis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|