F62. RISKY DECISION-MAKING PERFORMANCE IN PATIENTS WITH EARLY SCHIZOPHRENIA-SPECTRUM DISORDER

Autor: Eric Yh Chen, Wing Chung Chang, Sin Ki Luk, Tatia M.C. Lee
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Schizophrenia Bulletin
ISSN: 1745-1701
0586-7614
Popis: Background Dysfunction in risky decision-making has been regarded as one potential contributing factor to functional impairment exhibited in patients with schizophrenia. Literature has revealed suboptimal risky decision-making in chronic schizophrenia patients. However, abnormality in risky decision-making has not been investigated in the early stage of illness. This study aimed to examine whether early schizophrenia patients displayed aberrant risky decision-making using two well-validated paradigms including Balloon Analogue Risk Task (BART; Lejuez et al., 2002) and Risky-Gains Task (RGT; Paulus et al., 2003). Methods Thirty-three clinically-stable patients diagnosed with DSM-V schizophrenia-spectrum disorder (including schizophrenia, schizoaffective disorder or schizophreniform disorder) were recruited from specialized early intervention service for psychosis in Hong Kong. A group of healthy controls (n=32), matched with age, gender and educational levels, was enrolled for comparison. All participants were evaluated with a brief battery of cognitive assessment and two computerized risky decision-making tasks. Symptom assessment was also conducted for patients. Results In both BART and RGT, patients with early schizophrenia-spectrum disorder performed worse than healthy controls regarding total points gained and reaction time. In BART, patients had significantly lower adjusted scores (F(1,63)=7.8, p
Databáze: OpenAIRE