Design, synthesis, and bioimaging applications of a new class of carborhodamines
| Autor: | Hu Shi, Xia Yuan, Xin Lv, Wei Guo, Taihe Han |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Materials science
010405 organic chemistry Singlet oxygen medicine.medical_treatment Photodynamic therapy Nanotechnology 010402 general chemistry 01 natural sciences Biochemistry Fluorescence 0104 chemical sciences Analytical Chemistry Mitochondria chemistry.chemical_compound Design synthesis chemistry Photochemotherapy Electrochemistry medicine Environmental Chemistry hormones hormone substitutes and hormone antagonists Spectroscopy Fluorescent Dyes |
| Zdroj: | The Analyst. 146(1) |
| ISSN: | 1364-5528 |
| Popis: | We herein developed a new class of carborhodamines (CRs), i.e. 10-methoxy-substituted carborhodamines MCRs, by a simple synthesis procedure, which have absorption and emission wavelengths longer than classical CRs while retaining their excellent photophysical properties. Based on the MCR platform, we constructed the mitochondria-targeted fluorescent probe MCR-DMA and demonstrated its potential for sensing singlet oxygen (1O2) in living cells during the photodynamic therapy process. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|