Cuticle formation in parasitic nematodes: Ultrastructure of molting and the effects of actinomycin-D
| Autor: | Thomas P. Bonner, Lee N. Minier |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Ancylostomatoidea
Amanitins Nucleolus Golgi Apparatus Biology Endoplasmic Reticulum Animals Nippostrongylus brasiliensis Molecular Biology Cuticle (hair) Inclusion Bodies Vesicle Endoplasmic reticulum Cell Membrane Anatomy biology.organism_classification Cell biology Epidermis (zoology) Larva Protein Biosynthesis Dactinomycin Ultrastructure Nippostrongylus Moulting Cell Nucleolus |
| Zdroj: | Journal of Ultrastructure Research. 53:77-86 |
| ISSN: | 0022-5320 |
| DOI: | 10.1016/s0022-5320(75)80087-6 |
| Popis: | The ultrastructure of cuticle formation and the effect of actinomycin-D on cuticle formation were examined in the second molt of Nippostrongylus brasiliensis . At the end of the first molt the rough endoplasmic reticulum of the hypodermis (epidermis) had narrow cisternae. As cuticle formation began the RER cisternae dilated and accumulated a fibrous material. These large fibrous material-containing vesicles then decreased and by the time cuticle deposition was completed they had disappeared. Actinomycin-D prevented the proliferation of RER and the formation of fibrous material-containing vesicles. Actinomycin-D induced several ultrastructural alterations in the hypodermis, the most prominent of which were large crystalline-like inclusions. Other alterations involved the configuration of RER and structure of nucleoli. These morphological aspects of cuticle formation were correlated to the molecular events that control molting. |
| Databáze: | OpenAIRE |
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