Post-stapedotomy reparative granuloma following use of acellular porcine small intestinal submucosa
Autor: | Robert S. Hong, Talha U. Ghazi, Pedrom C. Sioshansi |
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Rok vydání: | 2021 |
Předmět: |
Reoperation
medicine.medical_specialty Swine Hearing loss medicine.medical_treatment Transplantation Heterologous Stapes Surgery 03 medical and health sciences Postoperative Complications 0302 clinical medicine Otology Vertigo Intestine Small otorhinolaryngologic diseases medicine Animals Humans Intestinal Mucosa Hearing Loss 030223 otorhinolaryngology Stapes Granuloma biology business.industry Middle Aged Stapedectomy biology.organism_classification medicine.disease Surgery Treatment Outcome medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis Middle ear Female medicine.symptom business |
Zdroj: | American Journal of Otolaryngology. 42:102933 |
ISSN: | 0196-0709 |
DOI: | 10.1016/j.amjoto.2021.102933 |
Popis: | Purpose There have been multiple proposed etiologies of reparative granuloma following stapes surgery. In this report, we present the first case of post-stapedectomy reparative granuloma following the use of Biodesign (Cook Medical, Bloomington, IN) otologic graft material, an acellular matrix derived from porcine small intestinal submucosa, and review the literature of post-stapes surgery reparative granuloma. Patient 50-year-old woman who developed a reparative granuloma following stapedotomy with acellular porcine intestinal submucosa presenting with profound hearing loss and vertigo. Intervention Middle ear exploration with excision of granuloma and revision stapedotomy. Main outcome measures Audiologic outcomes as measured by pure-tone air and bone conduction thresholds and word recognition scores. Improvement in vertigo. Main findings Surgical excision of the reparative granuloma with revision stapedotomy resolved vertigo. Hearing has improved progressively postoperatively. Conclusions We report the first case of post-stapedotomy reparative granuloma following the use of acellular porcine intestinal submucosa. Although exact etiology cannot be determined from a single case report, this illustrates the need for careful use of novel foreign graft material. This case additionally confirms that removal of granuloma and inciting materials can salvage serviceable hearing. |
Databáze: | OpenAIRE |
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