Post-stapedotomy reparative granuloma following use of acellular porcine small intestinal submucosa

Autor: Robert S. Hong, Talha U. Ghazi, Pedrom C. Sioshansi
Rok vydání: 2021
Předmět:
Zdroj: American Journal of Otolaryngology. 42:102933
ISSN: 0196-0709
DOI: 10.1016/j.amjoto.2021.102933
Popis: Purpose There have been multiple proposed etiologies of reparative granuloma following stapes surgery. In this report, we present the first case of post-stapedectomy reparative granuloma following the use of Biodesign (Cook Medical, Bloomington, IN) otologic graft material, an acellular matrix derived from porcine small intestinal submucosa, and review the literature of post-stapes surgery reparative granuloma. Patient 50-year-old woman who developed a reparative granuloma following stapedotomy with acellular porcine intestinal submucosa presenting with profound hearing loss and vertigo. Intervention Middle ear exploration with excision of granuloma and revision stapedotomy. Main outcome measures Audiologic outcomes as measured by pure-tone air and bone conduction thresholds and word recognition scores. Improvement in vertigo. Main findings Surgical excision of the reparative granuloma with revision stapedotomy resolved vertigo. Hearing has improved progressively postoperatively. Conclusions We report the first case of post-stapedotomy reparative granuloma following the use of acellular porcine intestinal submucosa. Although exact etiology cannot be determined from a single case report, this illustrates the need for careful use of novel foreign graft material. This case additionally confirms that removal of granuloma and inciting materials can salvage serviceable hearing.
Databáze: OpenAIRE