O-nucleophilic amino alcohol acyl-transfer catalysts: the effect of acidity of the hydroxyl group on the activity of the catalyst
| Autor: | Kjirsten A. Wayman, Tarek Sammakia |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
inorganic chemicals
Magnetic Resonance Spectroscopy Hydrocarbons Fluorinated Molecular Structure organic chemicals Organic Chemistry Carboxylic Acids Aminopyridines Alcohol Biochemistry Medicinal chemistry Amino Alcohols Catalysis chemistry.chemical_compound Kinetics Nucleophile chemistry Group (periodic table) Benzene Derivatives Organic chemistry heterocyclic compounds Physical and Theoretical Chemistry |
| Zdroj: | Organic letters. 5(22) |
| ISSN: | 1523-7060 |
| Popis: | [reaction: see text]. Amino alcohol-derived acyl-transfer catalysts are shown to operate by an O-nucleophilic mechanism, and catalysts bearing electron-withdrawing groups in proximity to the hydroxyl group are found to be more active. This is attributed to an increase in the acidity of the hydroxyl group of the catalyst. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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