Differences in Inflammation, Treatment, and Outcomes Between Black and Non-Black Patients Hospitalized for COVID-19: A Prospective Cohort Study
| Autor: | Husam Shadid, Abbas Bitar, Rafey Feroze, Patrick O'Hayer, Tariq U. Azam, John M. Carethers, Michael Pan, Penelope Blakely, Hanna Berlin, Chelsea Meloche, Kishan Padalia, Cristen J. Willer, Erinleigh Michaud, Elizabeth Anderson, Christopher Launius, Salim S. Hayek, Rodica Pop-Busui |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Coronavirus disease 2019 (COVID-19) medicine.medical_treatment remdesivir Inflammation corticosteroids Cohort Studies Diabetes mellitus Internal medicine medicine Humans Renal replacement therapy Prospective Studies Healthcare Disparities Prospective cohort study SARS-COV-2 Coronavirus disparities Aged African Americans SARS-CoV-2 business.industry Racial Groups M2C2 COVID-19 General Medicine Health Status Disparities Clinical Research Study Convalescent serum Middle Aged medicine.disease Obesity Hospitals United States Clinical trial Black or African American Hospitalization C-Reactive Protein Treatment Outcome Racial differences Female medicine.symptom business |
| Zdroj: | The American Journal of Medicine |
| ISSN: | 1555-7162 |
| Popis: | Purpose Racial disparities in COVID-19 outcomes have been described. We sought to determine whether differences in inflammatory markers, use of COVID-19 therapies, enrollment in clinical trials, and in-hospital outcomes contribute to racial disparities between Black and non-Black patients hospitalized for COVID-19. Methods We leveraged a prospective cohort study which enrolled 1325 consecutive patients hospitalized for COVID-19, of whom 341 (25.7%) were Black. We measured biomarkers of inflammation and collected data on the use COVID-19-directed therapies, enrollment in COVID-19 clinical trials, mortality, need for renal replacement therapy, and need for mechanical ventilation. Results Compared to non-Black patients, Black patients had a higher prevalence of COVID-19 risk factors including obesity, hypertension, and diabetes mellitus, and were more likely to require renal replacement therapy (15.8% vs. 7.1%, P |
| Databáze: | OpenAIRE |
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