Maximal exercise performance in chronic hypoxia and acute normoxia in high-altitude natives
| Autor: | Bengt Kayser, Hans Hoppeler, Hilde Spielvogel, Dominique Desplanches, Guido Ferretti, Roland Favier |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Exercise/ physiology Male medicine.medical_specialty Body Composition/physiology Physiology Acclimatization Oxygen Consumption/physiology Electrocardiography Oxygen Consumption Heart Rate Physiology (medical) Internal medicine Humans Medicine Exercise physiology Hypoxia Exercise Pulmonary Gas Exchange business.industry Altitude musculoskeletal neural and ocular physiology VO2 max Effects of high altitude on humans Hypoxia (medical) Chronic hypoxia ddc:616.8 Respiratory Function Tests Anoxia/ physiopathology Acute exposure Chronic Disease Body Composition Exercise Test Cardiology Pulmonary Gas Exchange/physiology Bicycle ergometer Blood Gas Analysis Maximal exercise medicine.symptom Acclimatization/physiology business human activities Heart Rate/physiology |
| Zdroj: | Journal of Applied Physiology: Respiratory, Environmental & Exercise Physiology, Vol. 78, No 5 (1995) pp. 1868-1874 Europe PubMed Central |
| ISSN: | 1522-1601 8750-7587 0161-7567 |
| Popis: | Maximal O2 uptake (VO2max) was determined on a bicycle ergometer in chronic hypoxia (CH) and during acute exposure to normoxia (AN) in 50 healthy young men who were born and had lived at 3,600 m altitude (La Paz, Bolivia). VO2max was significantly improved (approximately 8%) by AN. However, the difference in VO2max measured in CH and AN (delta VO2max) was lower than that reported in sea-level natives (SN) who exercised in chronic normoxia and acute hypoxia. It is shown that high-altitude natives (HN) and SN have a similar VO2max in normoxia, but highlanders can attain a greater VO2max when O2 availability is reduced by altitude exposure. In addition, in HN, the higher the subject's VO2max in hypoxia, the smaller his delta VO2max. These results contrast with the data obtained in 14 lowlanders acclimatized to high altitude who showed that their delta VO2max was positively related to their VO2max in hypoxia, as previously reported in SN who exercised in acute hypoxia (A. J. Young, A. Cymerman, and R. L. Burse. Eur. J. Appl. Physiol. Occup. Physiol. 54: 12–15, 1985). Furthermore, arterial O2 saturation of HN behaved differently from acclimatized lowland natives, inasmuch as it fell less during exercise both in CH and AN. HN with high aerobic capacity display a lower exercise ventilation and a reduced arterial saturation, which could explain their inability to improve VO2max with normoxia.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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