Major postoperative complications and survival for colon cancer elderly patients
| Autor: | Grosso, G, Biondi, Antonio Giuseppe, Marventano, S, Mistretta, Antonio, Calabrese, G, Basile, Francesco, Grosso, Giuseppe |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Colorectal cancer medicine.medical_treatment lcsh:Surgery Postoperative Complications Risk Factors medicine Odds Ratio Humans Laparoscopy Survival rate Colectomy Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry Age Factors Retrospective cohort study lcsh:RD1-811 General Medicine Odds ratio Middle Aged medicine.disease Surgery Survival Rate Treatment Outcome Multivariate Analysis Life expectancy Female business Complication Colorectal Neoplasms Research Article |
| Zdroj: | BMC Surgery BMC Surgery, Vol 12, Iss Suppl 1, p S20 (2012) |
| ISSN: | 1471-2482 |
| Popis: | Background Increased life expectancy has led to elevating the mean age of the patients at the time of diagnosis of colon cancer and subsequent treatment. Differences in complication rates and outcome between elderly and younger patients have been investigated. Methods We retrospectively analysed a database containing the information of patients who underwent surgery for stage I-III colorectal cancer from January 2004 to January 2012 at our institution and compared demographic, cancer-related, and outcomes data of 235 elderly patients with 211 patients ≤65 years old. Results Intraoperative complications did not differ between young and old patients whereas some differences have been found in postoperative and late complications: elderly patients suffered more by ileus (P = 0.024), peritonitis or septic shock (P = 0.017), pelvic abscess (P = 0.028), wound infection (P = 0.031), and incisional/port herniation (P = 0.012) compared with younger patients. Moreover, elderly patients suffered by systemic complications such as cardiovascular (4.7% vs. 1.4%, P = 0.049), renal (4.7% vs. 0.5%, P = 0.006), and respiratory (10.6% vs. 5.2%, P = 0.036). The multivariate analysis assessing the odds of having a complication revealed that older age (Odd Ratio [OR] 2.75, 95% Confidential Interval [CI]: 1.67-4.52) and open surgery (OR 1.63, 95% CI: 1.01-2.62) are significantly and independently associated with having a complication. Conclusions In our series, elderly patients have presented a slight higher incidence of comorbidities that may affect the incidence rates of postoperative complications. These results have implications in increasing the hospital stay as well as a higher rate of death. |
| Databáze: | OpenAIRE |
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