Clinical traits of patients with major depressive disorder with comorbid borderline personality disorder based on propensity score matching
| Autor: | Gao Xia, Ping Tong, Ping Bo, Ting Sun, Liping Dong, Yang Yang, Yuanhong Shi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Comorbidity
behavioral disciplines and activities 03 medical and health sciences 0302 clinical medicine Borderline Personality Disorder mental disorders medicine Humans Propensity Score Borderline personality disorder Modified Overt Aggression Scale Retrospective Studies Depressive Disorder Major Aggression business.industry Odds ratio medicine.disease 030227 psychiatry Psychiatry and Mental health Clinical Psychology Impulsive Behavior Propensity score matching Major depressive disorder Anxiety Age of onset medicine.symptom business 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Depression and Anxiety. 38:100-106 |
| ISSN: | 1520-6394 1091-4269 |
| Popis: | Background Major depressive disorder (MDD) with comorbid borderline personality disorder (BPD) makes the clinical symptoms of patients more complex and more difficult to treat, so more attention should be paid to the recognition of their clinical features. This study investigated the differences between patients with MDD with and without BPD in clinical traits. Methods Propensity score matching was used to analyze the retrospective patients' data from August 2012 to September 2019. Altogether, 1381 patients with MDD were enrolled; 38 patients with MDD were matched to compare demographic data, and scores on the Hamilton Depression Scale, Hamilton Anxiety Scale (HAMA), Self-Rating Depression Scale (SDS), Modified Overt Aggression Scale (MOAS), and the frequency of nonsuicidal self-harm (NSSH). Results Compared to patients with MDD without BPD, the age of onset of patients with MDD with comorbid BPD was significantly earlier (t = 3.25, p = .00). The scores of HAMA (t = -2.28, p = .03), SDS (t = 9.31, p = .00), MOAS (t = -13.67, p = .00), verbal aggression (t = -3.79, p = .00), aggression against objects (t = -2.84, p = .00), aggression against others (t = -6.70, p = .00), and aggression against self (t = -9.22, p = .00) were significantly higher in patients with MDD with comorbid BPD. Moreover, the frequency of NHSS in these patients was significantly higher (χ2 = 20.13, p = .00). MOAS was an independent influencing factor in these (odds ratio = 7.38, p = .00). Conclusions Patients with BPD showed early onset and increased complaints relative to symptoms, accompanied by obvious anxiety symptoms, impulsive behavior, and NSSH. Therefore, patients with MDD with impulsive behavior have comorbid BPD. |
| Databáze: | OpenAIRE |
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