Light-Driven Reductive Cleavage of Sulfonamides Promoted by Thiourea Organophotosensitizers

Autor:	Jules Brom, Antoine Maruani, Laurent Micouin, Erica Benedetti
Rok vydání:	2023
Předmět:	Organic Chemistry
Zdroj:	The Journal of Organic Chemistry. 88:5923-5935
ISSN:	1520-6904 0022-3263
DOI:	10.1021/acs.joc.3c00296
Popis:	We have developed a practical method to perform the reductive photocleavage of sulfonamides using thioureas as organophotocatalysts. This transformation, which tolerates a variety of substrates, occurs under mild reaction conditions in the presence of tetrabutylammonium borohydride as a reducing agent. Experimental and theoretical mechanistic investigations complete the study, shedding light on the nature of the active species involved in the photocatalytic process.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4245b74b8c0df6c6a8bef541f2df2cd4 https://doi.org/10.1021/acs.joc.3c00296 Zobrazit plný text záznamu