Supplementary Figures S1-8 from Ultra-Sensitive Detection of the Pretreatment EGFR T790M Mutation in Non–Small Cell Lung Cancer Patients with an EGFR-Activating Mutation Using Droplet Digital PCR

Autor: Yasuhiro Koh, Akihide Matsumura, Kazuhiro Sakamoto, Yukiyasu Takeuchi, Yukito Ichinose, Kazuhiko Kataoka, Motohiro Yamashita, Seiichi Kakegawa, Tsutomu Tagawa, Hirofumi Adachi, Sadanori Takeo, Hideo Saka, Akihito Kubo, Akihiro Tamiya, Masahiko Ando, Shun-ichi Isa, Tomoya Kawaguchi, Masaru Watanabe
Rok vydání: 2023
Popis: Supplementary Figures S1-8. Figure S1: Flowchart for mutation call. Figure S2: Quantification of performance of ddPCR analysis for EGFR T790M mutation. Figure S3: Analytical sensitivity of 0.001% for the ddPCR assay. Figure S4: Determination of false-positive events from wild-type control DNA and normal human genomic DNA. Figure S5: Determination of false-positive events in genomic DNA from formalin-fixed paraffin-embedded (FFPE) A549 cells. Figure S6: Detection of EGFR T790M mutant alleles in patients with EGFR T790M-containing primary tumors. Figure S7: Comparison of T790M mutation detection in 6 samples by different operators. Figure S8: Reproducibility of ddPCR analysis from 16 T790M-positive samples.
Databáze: OpenAIRE