Transmuscular quadratus lumborum block for postoperative pain and recovery after laparoscopic adrenalectomy: a randomized controlled trial
Autor: | Yushi Zhang, Lu Sufang, Yuelun Zhang, Yuguang Huang, Zhigang Ji, Yi Xie, Qing Yuan, Weigang Yan, Xu-lei Cui |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male Time Factors Nausea Laparoscopic adrenalectomy Pain Placebo Fentanyl law.invention Patient satisfaction Double-Blind Method Randomized controlled trial Anesthesiology law medicine Clinical endpoint Humans Ropivacaine RD78.3-87.3 Prospective Studies Anesthetics Local Pain Measurement Pain Postoperative business.industry Research Adrenalectomy Nerve Block Middle Aged Analgesics Opioid Anesthesiology and Pain Medicine Patient Satisfaction Anesthesia Female Laparoscopy Tramadol medicine.symptom business Transmuscular quadratus lumborum block medicine.drug |
Zdroj: | BMC Anesthesiology, Vol 21, Iss 1, Pp 1-8 (2021) BMC Anesthesiology |
ISSN: | 1471-2253 |
Popis: | Background To investigate the role of transmuscular quadratus lumborum block (TMQLB) for postoperative pain control, patient satisfaction and recovery in laparoscopic adrenalectomy. Methods Seventy-two patients aged between 18 and 70 years with an ASA I-II and scheduled for laparoscopic adrenalectomy were randomized to receive a single-shot TMQLB with 0.4 ml/kg 0.5 % ropivacaine or 0.4 ml/kg 0.9 % saline as placebo. The primary endpoint was pain on movement at 12 h after surgery evaluated by the numeric rating scale (NRS, 0–10). P-values Results NRS on movement at 12 h after surgery was lower in the TMQLB group compared with the control (median 2 vs. 3, p = 0.024). Intraoperative fentanyl consumption was lower in the TMQLB group (247.08 ± 63.54 vs. 285.44 ± 74.70, p = 0.022). The rate of using postoperative rescue tramadol was also lower in the TMQLB group (5.6 vs. 27.8 %, p = 0.027). Similar incidences of nausea and vomiting were observed (11.1 vs. 25 %, p = 0.220). Patient satisfaction of pain service was better in the TMQLB group (83.3 vs. 25 %, p p = 0.004) and flatus (18.5 vs. 23.5 h, p = 0.006). Conclusions TMQLB showed better control of postoperative pain on movement for laparoscopic adrenalectomy with improved patients’ satisfaction of anesthesia, shorter time to ambulation and flatus. Trial registration This study was registered at Clinicaltrials.gov (NCT03942237; registration date: 08/05/2019; enrollment date: 10/05/2019). |
Databáze: | OpenAIRE |
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