Efficacy of local salvage therapy for recurrent uterine cervical cancer after definitive radiotherapy
| Autor: | Noriko Kishi, Aya Nakajima, Shinya Hiraoka, Takashi Mizowaki, Yukinori Matsuo, Hideki Hanazawa, Keiichi Takehana |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Uterine cervical cancer medicine.medical_treatment Uterine Cervical Neoplasms Salvage therapy 03 medical and health sciences 0302 clinical medicine Surgical oncology medicine Humans Lymph node Retrospective Studies Salvage Therapy Chemotherapy business.industry Medical record Chemoradiotherapy Hematology General Medicine Prognosis Surgery Radiation therapy 030104 developmental biology medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Carcinoma Squamous Cell Female Neoplasm Recurrence Local business |
| Zdroj: | International Journal of Clinical Oncology. 26:1968-1976 |
| ISSN: | 1437-7772 1341-9625 |
| Popis: | The prognosis of patients with recurrence of uterine cervical cancer after definitive radiotherapy and the efficacy of local salvage therapy for recurrence were evaluated. We retrospectively reviewed 110 patients who were treated with definitive radiotherapy/chemoradiotherapy for uterine cervical cancer between 2008 and 2017 at our institution. Local salvage therapy was defined as any surgery or radiotherapy described in the medical record as intended for local control or cure. We identified 25 patients who developed recurrence after definitive radiotherapy/chemoradiotherapy. The median follow-up time post-recurrence was 18.9 months. Thirteen patients (52%) reported recurrence in the isolated extra-pelvic lymph node (EPLN). The 2-year overall survival after first recurrence (OSr) for patients with isolated EPLN recurrence was 83.1%, compared to that of 31.2% for patients with other patterns of recurrence (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink