Cubic spline for the association between OPN levels and HCC from Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population

Autor: Laura Beretta, Pierre Hainaut, Mazda Jenab, Elio Riboli, Amanda J. Cross, Marc J. Gunter, Kathryn E. Bradbury, Kay-Tee Khaw, Nicholas J. Wareham, Klas Sjöberg, Bodil Ohlsson, Oskar Hemmingsson, Mårten Werner, Miren Dorronsoro, Diana Gavrila, Eva Ardanaz, Emilio Sánchez-Cantalejo, Antonio Agudo, J. Ramón Quirós, Elisabete Weiderpass, Petra H. Peeters, H.B(as). Bueno-de-Mesquita, Alessio Naccarati, Rosario Tumino, Amalia Mattiello, Domenico Palli, Valeria Pala, Christina Bamia, Pagona Lagiou, Antonia Trichopoulou, Krasimira Aleksandrova, Heiner Boeing, Rudolf Kaaks, Renee Turzanski-Fortner, Marie-Christine Boutron-Ruault, Gianluca Severi, Laura Baglietto, Anne Tjønneland, Anja Olsen, Kim Overvad, David Muller, Amelie Plymoth, Magdalena Stepien, Sandeep Misra, Talita Duarte-Salles
Rok vydání: 2023
DOI: 10.1158/1940-6207.22534384.v1
Popis: Multivariable adjusted odds ratio (continuous line) and 95% CI (dotted line) are shown for the continuous levels of OPN values associated to HCC. Reference value was set at 47.15 ng/ml (the optimal cut-off point) for all subjects. For better visibility, the levels were truncated at 1 and 99 percentile of distribution.
Databáze: OpenAIRE