Adenocarcinomas of esophagus and cardia in comparison with gastric carcinoma
| Autor: | G. Heidl, W. Mellin, P. Langhans, E. Grundmann, H. Bünte |
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| Rok vydání: | 1993 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Pathology Esophageal Neoplasms Gastric carcinoma Adenocarcinoma Adenoid Age and sex Gastroenterology Age Distribution Stomach Neoplasms Internal medicine otorhinolaryngologic diseases medicine Carcinoma Humans Sex Distribution Esophagus Aged Retrospective Studies Esophageal disease business.industry Stomach Cardia General Medicine Middle Aged medicine.disease digestive system diseases medicine.anatomical_structure Oncology Lymphatic Metastasis Carcinoma Squamous Cell Female business |
| Zdroj: | Journal of Cancer Research and Clinical Oncology. 120:95-99 |
| ISSN: | 1432-1335 0171-5216 |
| DOI: | 10.1007/bf01200731 |
| Popis: | Since the carcinomas of the cardia and the adenocarcinomas of the esophagus show many similarities in their histological and morphological descriptions, a detailed comparative study was attempted on the basis of 66 esophageal carcinomas in adenoid differentiation, 359 carcinomas of the cardia, 1288 gastric carcinomas in infracardial localisation, and 492 squamous carcinomas of the esophagus. The evaluation yielded no significant differences between the adenocarcinomas of the esophagus and the cardia neither in age and sex distribution nor with regard to the classifications of Borrmann, WHO, Ming, and Laurén, but a significant discrimination was possible between esophageal and cardial adenocarcinoma together, on the one hand, and infracardial gastric carcinoma on the other. Furthermore, esophageal adenocarcinomas were localized preferentially in the lower third, unlike squamous carcinomas of the same organ. These results suggest that esophageal adenocarcinoma and carcinoma of the cardia must be considered as one separate entity, probably originating from a common stem cell. They further suggest that the cardia belongs to the esophagus rather than to the stomach. |
| Databáze: | OpenAIRE |
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