New, Scalable Route for the Synthesis of a trans-Fused Hexahydro-1H-phenanthren-2-one from a Conjugated Tetrahydro-3H-phenanthren-2-one

Autor:	Morgan Bradley P, Richard V. Trilles, Graeme F. Woodworth
Rok vydání:	2003
Předmět:	chemistry.chemical_classification Hydrogen Double bond Stereochemistry Chemistry Organic Chemistry chemistry.chemical_element Moiety Stereoselectivity General Medicine Conjugated system Combinatorial chemistry
Zdroj:	ChemInform. 34
ISSN:	1522-2667 0931-7597
Popis:	A three-step, readily scalable route for the conversion of a ring-conjugated tetrahydro-3H-phenanthren-2-one to a trans-fused hexahydro-1H-phenanthren-2-one is described. The key step is the hydrogenation of a double bond using a nearby ketal moiety to assist in the stereoselective delivery of the hydrogen.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4225cfaeaf8486cc21c28dde2fba92b0 https://doi.org/10.1002/chin.200333186 Zobrazit plný text záznamu Plný text