Determinants of short term fracture risk in patients with a recent history of low-trauma non-vertebral fracture
| Autor: | Aude Deloumeau, Karine Briot, Anna Molto, Christian Roux |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Fracture risk
Male medicine.medical_specialty Histology Time Factors Physiology Endocrinology Diabetes and Metabolism Osteoporosis 030209 endocrinology & metabolism Disease cluster 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Medicine Humans 030212 general & internal medicine Femoral neck Bone mineral Hip fracture business.industry Hip Fractures Middle Aged medicine.disease Surgery medicine.anatomical_structure Orthopedic surgery Multivariate Analysis Fracture (geology) Female business Osteoporotic Fractures |
| Zdroj: | Bone. 105 |
| ISSN: | 1873-2763 |
| Popis: | Low-trauma fractures tend to cluster in time, and subsequent fractures have a role in increased morbidity and mortality in osteoporotic patients. The aim of this study was to identify the risk factors of short-term subsequent non-vertebral fracture (NVF). Patients were included from the Fracture Liaison Service (FLS) which provides assessment for osteoporosis to all in-hospital patients admitted for a low-trauma NVF in the Orthopaedics department. Location and date of occurrence of previous fractures, risk factors for osteoporosis and falls were collected. Bone mineral density was measured at the lumbar spine and total hip; presence of vertebral fractures was evaluated using vertebral fracture assessment (VFA). Nine hundred and fifty patients were included (84% women; 75 ± 12 years), with a mean T-score at the femoral neck of − 2.3 ± 1.0. Four hundred and sixty eight (49%) patients were in the FLS because of a hip fracture. Using multivariable analysis, the risk of being in the FLS with a previous fracture ≤ 3 years before was associated with: history of fall in the year before the admission (OR = 2.75, CI 95% 1.55–4.93), history of severe low-trauma NVF (OR = 2.54; CI 95% 1.45–4.52), and BMI lower than 20 kg/m2 (OR = 2.45, CI 95% 1.25–4.87); age older than 78 years-old was protective to the risk of re-fracture (OR = 0.44, CI 95% 0.24–0.80). Some risk factors (age, history of fall and of previous severe non-vertebral fracture) can help in the selection of patients at high risk of refracture, who should receive the highest priority for a treatment. |
| Databáze: | OpenAIRE |
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