Multichannel functional testing in normal subjects, glaucoma suspects, and glaucoma patients
| Autor: | María José Luque, A. Felipe, Antonio Morilla-Grasa, Pascual Capilla, Alfonso Antón, José María Artigas |
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| Předmět: |
Adult
Male medicine.medical_specialty genetic structures Functional testing Glaucoma Audiology Cycles per degree Contrast Sensitivity Pattern standard deviation Ojos--Enfermedades Reference Values Ophthalmology Optic Nerve Diseases Medicine Humans Prospective Studies Intraocular Pressure Aged business.industry Vision Tests Reproducibility of Results Middle Aged medicine.disease Normal limit eye diseases medicine.anatomical_structure Cross-Sectional Studies Multicenter study Oftalmologia Eye--Diseases Optic nerve Oftalmología Female Ocular Hypertension sense organs Visual Fields business Ulls--Malalties Color Perception Optic disc |
| Zdroj: | Recercat. Dipósit de la Recerca de Catalunya instname |
| Popis: | Purpose.: To evaluate visual function with a novel multichannel functional test named the ATD Multichannel Functional Test. Methods.: This multicenter study had a prospective and cross-sectional design. A total of 186 eyes were included: 42 with glaucoma, 14 glaucoma suspects due to optic nerve characteristics, 25 ocular hypertensives, and 105 normal eyes. All patients performed standard visual fields (Humphrey 24-2) and ATD with eight stimuli configurations: four achromatic (A), two red-green (T), and two blue-yellow (D). To derive main outcome measures, mean sensitivity, mean defect (MD), and pattern standard deviation (PSD) were calculated and compared among groups and types of stimuli with the Kruskal-Wallis test. The percentage of cases outside normal limits (ONL) was calculated. Results.: MD and PSD were significantly different in glaucoma eyes than in normal subjects for all types of stimuli except D-0.5 cycles per degree (cpd)/12Hz. PSD was also lower for normals than for all pathologic groups with A-4cpd/2Hz, A-4cpd/12Hz, D-0.5cpd/2Hz, and T-0.5cpd/2Hz. The highest percentage of ONL cases was obtained with the two low-spatial-frequency chromatic stimuli, with D-0.5cpd/2Hz and T-0.5cpd/2Hz using PSD, which classified as ONL 81.6% and 86.7% of glaucoma eyes, 51.8% and 44.5% of hypertensives, and 72.2% and 41.2% of optic disc suspects, respectively. Conclusions.: ATD assessed different aspects of visual function, and the most sensitive tests to detect glaucomatous damage were the low-temporal-frequency chromatic tests. info:eu-repo/semantics/acceptedVersion |
| Databáze: | OpenAIRE |
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