| Autor: |
Ashish Jain, Rohit Jain, Rajeev Kasliwal, Priyamvada Gupta, Anand Jain, Divyansh Gupta, Srishti Suresh Jain, Rohan Tambi, Puneet Panwar, Munesh Meena, Ravi Jain |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine. 26(6) |
| ISSN: |
0972-5229 |
| Popis: |
End-organ damage in coronavirus disease-2019 (COVID-19) is linked to "cytokine storm" and excessive release of inflammatory mediators. Various novel therapies have been used in COVID-19 including urinary trypsin inhibitor therapy. This study explores the efficacy of ulinastatin in COVID-19.We retrieved the medical records of patients admitted during one month and did a propensity score analysis to create matched treatment and control groups. We analyzed these groups and the outcomes were presented with appropriate statistics. Survival curve was prepared to compare the survival effect of ulinastatin therapy at the end of hospitalization, among both the groups.A total of 736 patients were admitted, and after adjusting the data with propensity score matching, 55 cases were selected by the system. On the final outcome analysis, we found that intensive care unit (ICU) length of stay [median (interquartile range) days 3 (3.5-7.8) vs 2 (0-4);Jain A, Kasliwal R, Jain SS, Jain R, Gupta D, Gupta P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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