Java project on periodontal diseases: serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period
| Autor: | Ubele van der Velden, Wil A. van der Reijden, Arie Jan van Winkelhoff, C. J. Bosch-Tijhof |
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| Přispěvatelé: | Microbiologie (OUD, ACTA), Parodontologie (OUD, ACTA), Personalized Healthcare Technology (PHT) |
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Serotype Virulence Factors Population SERUM ANTIBODY FREQUENCY Aggregatibacter actinomycetemcomitans Polymerase Chain Reaction Microbiology PORPHYROMONAS-GINGIVALIS Periodontal Attachment Loss ADOLESCENTS Prevalence medicine Humans Aggressive periodontitis Prospective Studies Typing Promoter Regions Genetic education Porphyromonas gingivalis periodontitis POPULATION Sequence Deletion Periodontitis Molecular Epidemiology education.field_of_study biology STABILITY business.industry A. actinomycetemcomitans ACQUISITION AGGRESSIVE PERIODONTITIS medicine.disease biology.organism_classification serotyping Clinical attachment loss Indonesia Periodontics Female business LOCALIZED JUVENILE PERIODONTITIS ACTINOBACILLUS-ACTINOMYCETEMCOMITANS |
| Zdroj: | Journal of Clinical Periodontology, 35(6), 487-492. Blackwell Munksgaard Journal of Clinical Periodontology, 35(6), 487-492. Wiley van der Reijden, W A, Bosch-Tijhof, C J, van der Velden, U & van Winkelhoff, A J 2008, ' Java project on periodontal diseases: serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period ', Journal of Clinical Periodontology, vol. 35, no. 6, pp. 487-492 . https://doi.org/10.1111/j.1600-051X.2008.01218.x |
| ISSN: | 0303-6979 |
| Popis: | Objective: To investigate the serotype distribution and stability of Aggregatibacteractinomycetemcomitans over an 8-year period in untreated Indonesian subjects.Material and Methods: Clinical periodontal status and the presence ofA. actinomycetemcomitans were established in 1994 and 2002 in 107 subjects froman Indonesian tea estate deprived from dental care. On an average, 3.6 isolates perpatient were subcultured and serotyped using specific PCR reactions.Results: In 1994, the predominant serotype was b (53.7%), whereas a and c occurredin 17.1% and 14.6% of the subjects, respectively. In 2002, a reduction in serotypes a(7.5%) and b (30.2%) occurred. Serotypes c and e increased in prevalence from 14.6%to 35.8% and 2.4% to 9.4%, respectively. Multiple serotypes were found in 12.2%in 1994 and 17% in 2002. From 24 subjects who were positive at both time points,14 (58.3%) had the same serotype, whereas in 10 subjects (41.7%), a different serotypewas found. Mean clinical attachment loss had increased from 0.74mm in 1994 to1.96mm in 2002 but could not be related to subgingival presence of A. actinomycetemcomitans.Conclusions: A. actinomycetemcomitans serotypes distribution in Indonesian youngadults shifts from predominantly serotype b to a more equal prevalence of serotypes band c. This shift suggests an opportunistic character of A. actinomycetemcomitans. |
| Databáze: | OpenAIRE |
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