Bacterial profile and antimicrobial susceptibility patterns in chronic suppurative otitis media at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia

Autor: Moges Tiruneh, Wondwossen Abebe, Feleke Moges, Rahel Molla
Jazyk: angličtina
Rok vydání: 2019
Předmět:
0301 basic medicine
Staphylococcus aureus
Erythromycin
lcsh:Medicine
Microbial Sensitivity Tests
Providencia
Hospitals
Special
Otitis Media
Suppurative
General Biochemistry
Genetics and Molecular Biology
Microbiology
Hospitals
University
03 medical and health sciences
0302 clinical medicine
Ciprofloxacin
Clarithromycin
medicine
Tobramycin
Humans
030212 general & internal medicine
Antimicrobial susceptibility patterns
lcsh:Science (General)
Proteus mirabilis
lcsh:QH301-705.5
Norfloxacin
Bacteria
biology
lcsh:R
Bacterial Infections
General Medicine
biochemical phenomena
metabolism
and nutrition
Chronic suppurative otitis media
biology.organism_classification
bacterial infections and mycoses
Anti-Bacterial Agents
Research Note
030104 developmental biology
lcsh:Biology (General)
Chronic Disease
Gentamicin
Ethiopia
Cefixime
medicine.drug
lcsh:Q1-390
Zdroj: BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
BMC Research Notes
ISSN: 1756-0500
Popis: Objectives This study aims to determine bacterial profile and antimicrobial susceptibility patterns of chronic suppurative otitis media in the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia. Result Sixty-two ear swabs were collected and 74 bacterial isolates were identified, of which 48 (77.4%) sample with mono-microbial growth, 11 (17.8%) with polymicrobial growth and the remaining 3 (4.8%) show no growth. The most common isolates were Proteus mirabilis 16 (21.6%), followed by S. aureus 12 (16.2%), Klebsiella spp. 10 (13.5%) and Providencia spp. 11 (14.9%). Proteus mirabilis was 100% susceptible to norfloxacin and ciprofloxacin while 87.5% of the isolates were susceptible to cefixime and gentamicin. S. aureus was 83.3% susceptible to gentamicin and clarithromycin, while 75% of the isolates were susceptible to amoxicillin–clavulanic acid and chloramphenicol, however, 66.7% the isolates were susceptible to ciprofloxacin, norfloxacin and erythromycin. The overall prevalence of multidrug resistance in the current study was 35 (47.3%). In this study P. mirabilis, S. aureus, Providencia spp., and Klebsiella spp. were the most common bacterial isolate and all Gram negative isolates were susceptible to ciprofloxacin and norfloxacin. Amoxicillin–clavulanic acid, gentamicin, chloramphenicol, clarithromycin and tobramycin were relatively effective against Gram positive bacteria. Electronic supplementary material The online version of this article (10.1186/s13104-019-4452-4) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE
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